SIDE EFFECTS & SAFETY
When taken by mouth: Cannabidiol is POSSIBLY SAFE when taken by mouth or sprayed under the tongue appropriately. Cannabidiol in doses of up to 300 mg daily have been taken by mouth safely for up to 6 months. Higher doses of 1200-1500 mg daily have been taken by mouth safely for up to 4 weeks. A prescription cannabidiol product (Epidiolex) is approved to be taken by mouth in doses of up to 10-20 mg/kg daily. Cannabidiol sprays that are applied under the tongue have been used in doses of 2.5 mg for up to 2 weeks.
Some reported side effects of cannabidiol include dry mouth, low blood pressure, light headedness, and drowsiness. Signs of liver injury have also been reported in some patients, but this is less common.
When applied to the skin: There isn’t enough reliable information to know if cannabidiol is safe or what the side effects might be.
Special Precautions & Warnings:
Pregnancy and breast-feeding: Cannabidiol is POSSIBLY UNSAFE to use if you are pregnant or breast feeding. Cannabidiol products can be contaminated with other ingredients that may be harmful to the fetus or infant. Stay on the safe side and avoid use.
Children: A prescription cannabidiol product (Epidiolex) is POSSIBLY SAFE when taken by mouth daily. The most common dose used is 10 mg/kg daily. Higher doses of 15-20 mg/kg daily may be used in some children, but these higher doses are more likely to cause side effects. This product is approved for use in certain children 2 years of age and older, but has been used in children as young as 1 year of age.
Liver disease: People with liver disease may need to use lower doses of cannabidiol compared to healthy patients.